97 Grass Pollen Allergen-induced Surface Expression of CD203C, CD63 and CD107A on CRTH2+ Basophils: Novel Biomarkers for Monitoring Efficacy of Allergen-specific Immunotherapy
نویسندگان
چکیده
were either unresponsive or showed elevated mRNA levels of the Th1-promoting chemokines CXCL10 and CXCL11. Conclusions: This study supported by grant SFB-F1802 of the Austrian Science Fund shows for the first time that the allergen uptake is specific and similar in DCs from allergic and healthy individuals. More important, the ensuing signal cascade that is triggered by the allergen differs between DCs of the 2 donor groups and results in a Th2-polarized immune response in allergic individuals as compared to ignorance/tolerance in normal donor cells.
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عنوان ژورنال:
دوره 5 شماره
صفحات -
تاریخ انتشار 2012